Article ID Journal Published Year Pages File Type
1150003 Journal of Statistical Planning and Inference 2008 9 Pages PDF
Abstract
In the paper we present a new method of calculating sampling intervals, so-called windows, allowing an experimenter some flexibility in timing the sample collection, while a minimum required design efficiency for parameter estimation is assured. The method is based on the Equivalence Theorem for D-optimality what makes the length of each window related to the parameter sensitivities. An example of calculating the windows in a pharmacokinetic study is presented. Some other methods of calculating efficient sampling windows are briefly discussed.
Related Topics
Physical Sciences and Engineering Mathematics Applied Mathematics
Authors
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