Article ID Journal Published Year Pages File Type
1164449 Analytica Chimica Acta 2013 24 Pages PDF
Abstract

•Review on liquid chromatography coupled to post-column derivatization.•Overview of instrumentation for post-column derivatization.•Post-column chemistries for analysis of organic compounds.

Analytical derivatization either in pre or post column modes is one of the most widely used sample pretreatment techniques coupled to liquid chromatography. In the present review article we selected to discuss the post column derivatization mode for the analysis of organic compounds. The first part of the review focuses to the instrumentation of post-column setups including not only fundamental components such as pumps and reactors but also less common parts such as static mixers and back-pressure regulators; the second part of the article discusses the most popular “chemistries” that are involved in post column applications, including reagent-less approaches and new sensing platforms such as the popular gold nanoparticles. Some representative recent applications are also presented as tables.

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Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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