| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1164610 | Analytica Chimica Acta | 2013 | 7 Pages |
•A novel high-throughput device based on 96-μ-SPE system is introduced.•Dodecyl methacrylate-ethylene glycol dimethacrylate monolithic polymer is used as extractant.•The developed method was applied to multiresidue determination of nine pesticides in water.
A novel high-throughput device based on 96-micro-solid phase extraction (96-μ-SPE) system was constructed for multiresidue determination of nine pesticides in aquatic samples. The extraction procedure was performed on a commercially available 96-well plate system. The extraction module consisted of 96 pieces of 1 cm × 3 cm of cylindrically shaped stainless steel meshes. The prepared meshes were fixed in a home-made polytetrafluoroethylene-based constructed ninety-six holes block for possible simultaneous immersion of meshes into the center of individual wells. Dodecyl methacrylate and ethylene glycol dimethacrylate was copolymerized as a monolithic polymer and placed in the cylindrically shaped stainless steel meshes as extracting medium. A volume of 1 mL of the aquatic sample was transferred into the 96-well plate and the 96-μ-SPE device was applied for the extraction of the selected pesticides. Subsequently, the extracted analytes were analyzed by gas chromatography–mass spectrometry. Influential parameters such as polymer synthesis conditions, sorbent-to-sorbent reproducibility, ionic strength and extraction time were optimized. Intra and inter-sorbent reproducibility on 96-μ-SPE device were evaluated and results revealed that extraction yields are rather similar. Limits of detection were below 4 μg L−1 and the coefficient of determination was satisfactory (r2 > 0.99) for all the studied analytes. The developed method was successfully applied to the extraction and determination of the selected pesticides in surface water samples.
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