A novel superparamagnetic surface molecularly imprinted nanoparticle adopting dummy template: An efficient solid-phase extraction adsorbent for bisphenol A

Leakage of the residual template molecules is one of the biggest challenges for application of molecularly imprinted polymer (MIP) in solid-phase extraction (SPE). In this study, bisphenol F (BPF) was adopted as a dummy template to prepare MIP of bisphenol A (BPA) with a superparamagnetic core–shell nanoparticle as the supporter, aiming to avoid residual template leakage and to increase the efficiency of SPE. Characterization and test of the obtained products (called mag-DMIP beads) revealed that these novel nanoparticles not only had excellent magnetic property but also displayed high selectivity to the target molecule BPA. As mag-DMIP beads were adopted as the adsorbents of solid-phase extraction for detecting BPA in real water samples, the recoveries of spiked samples ranged from 84.7% to 93.8% with the limit of detection of 2.50 pg mL−1, revealing that mag-DMIP beads were efficient SPE adsorbents.

Graphical abstractBPF was adopted as a dummy template to prepare BPA-MIP with a superparamagnetic core–shell nanoparticle as the supporter, which was approved to be an efficient SPE adsorbent.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► BPF was used as a dummy template to prepare BPA-MIP. ► A superparamagnetic core–shell nanoparticle was designed as MIP supporter. ► A method for BPA extraction from water sample was provided. ► MIP bead was proved to be an efficient SPE adsorbent.