Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1171779 | Analytica Chimica Acta | 2006 | 5 Pages |
Abstract
A new post chemiluminescence (PCL) reaction was observed when atropine sulfate was injected into the reaction mixture after the finish of CL reaction of Ce(IV) and sodium sulfite. The possible mechanism for the PCL reaction was discussed via the investigation of the CL kinetic characteristics, the CL spectra, the UV absorption spectra and the fluorescence spectra of some related substances. The flow injection PCL method for the determination of atropine sulfate was established. The relative standard deviation (R.S.D.) was 2.8% (n = 11, c = 5.0 Ã 10â6 g mLâ1). The PCL intensity responded linearly to the concentration of atropine sulfate in the range 1.0 Ã 10â6 to 5.0 Ã 10â5 g mLâ1 with a linear correlation of 0.9947. The detection limit was 4 Ã 10â7 g mLâ1 atropine sulfate. The method had been applied to the determination of atropine sulfate in the tablets and the results were consistent with the method of Chinese pharmacopoeia.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Shuwen Sun, Jiuru Lu,