| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11927 | Biomaterials | 2005 | 7 Pages |
Abstract
A rapid, viable and safe fabrication method for biomaterials synthesis is reported using high-frequency AC electrospraying. We demonstrate its potential for polymeric nanoparticle fabrication, drug encapsulation in mono-dispersed micron-sized biodegradable polymer shells and the synthesis of 1 μm biodegradable fibers with adjustable pore sizes as bioscaffolds for tissue/orthopaedic engineering and wound care therapy. The absence of charge in the ejected drops and fibers facilitates pulmonary drug delivery, polymer encapsulation and minimizes protein/DNA denaturing or compound ionization.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Leslie Y. Yeo, Zachary Gagnon, Hsueh-Chia Chang,