| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11987988 | Biochemical and Biophysical Research Communications | 2018 | 7 Pages |
Abstract
Collectively, IR reduces Sfrp5 expression of lung tissue and activates the Wnt5a/JNK1 pathway, promoting macrophage activation and contributing to the lung's inflammatory response. In contrast, Sfrp5 suppresses the inflammatory response by inhibiting the Wnt5a/JNKl pathway, which could be a target of treatment of COPD.
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Authors
Zhen Zhu, Shaojun Yin, Kaiyue Wu, Amber Lee, Yi Liu, Hong Li, Shuang Song,