| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1271780 | Bioelectrochemistry | 2012 | 5 Pages |
Abstract
⺠PDDA/DNA/{HRP/DNA}2 layer-by-layer films are used to detect DNA damage by CV. ⺠DNA damage is caused by NO2
- radicals produced in situ with H2O2 + NO2â solutions. ⺠Catalase on surface of PDDA/DNA/{HRP/DNA}2 films can protect inside DNA from damage. ⺠This work provides a foundation for fabricating biosensors in detecting DNA damage. ⺠An in vitro model to simulate the pathway of DNA damage and protection is presented.
- radicals produced in situ with H2O2 + NO2â solutions. ⺠Catalase on surface of PDDA/DNA/{HRP/DNA}2 films can protect inside DNA from damage. ⺠This work provides a foundation for fabricating biosensors in detecting DNA damage. ⺠An in vitro model to simulate the pathway of DNA damage and protection is presented.
Related Topics
Physical Sciences and Engineering
Chemistry
Electrochemistry
Authors
Yan Zhang, Hongyun Liu, Naifei Hu,