Synthesis of polyacetylenic montiporic acids by means of organosilicon compounds

A straightforward synthesis of polyacetylenic montiporic acids A and B has been developed, based upon the selective and sequential substitution of the two trimethylsilyl groups of the readily available 1,4-bis(trimethylsilyl)-1,3-butadiyne.

Graphical abstractMontiporic acids A and B have been synthesized starting from the readily available 1,4-bis(trimethylsilyl)-1,3-butadiyne.Figure optionsDownload full-size imageDownload as PowerPoint slide