Interaction between aspergillic acid and iron(III): A potentiometric, UV–Vis, 1H NMR and quantum chemical study

The complex formation equilibria of aspergillic acid with iron(III) were studied by potentiometric and spectrophotometric methods. The ligand was prepared by a biosynthetic route and its purity checked by MS and 1H NMR spectroscopies. Some structural features of the ligand are discussed on the basis of NMR results. The iron(III) coordination model is compared with those of two other cyclic hydroxamates, 1-hydroxy-2-pyridinone and 1,4-dihydroxy-2-pyridinone, and its features are discussed on the basis of quantum chemical calculations.

Graphical abstractThe complex formation equilibria of aspergillic acid with iron(III) were studied potentiometrically and spectrophotometrically. Some structural features of ligand, prepared biosynthetically, are discussed on the basis of NMR results. Iron(III) coordination model is examined on the grounds of quantum chemical calculations and compared with those of two other cyclic hydroxamates.Figure optionsDownload full-size imageDownload as PowerPoint slide