Synthesis and physico-chemical studies on complexes of 1,2-diaminophenyl-N,N′-bis-(2-pyridinecarboxaldimine), (L): A spectroscopic approach on binding studies of DNA with the copper complex

The Schiff base ligand, 1,2-diaminophenyl-N,N′-bis-(2-pyridinecarboxaldimine), (L) has been synthesized by the reaction of o-phenylenediamine and 2-pyridinecarboxaldehyde, and a series of mononuclear complexes of the type [ML(NO3)2] [M = Co(II), Ni(II), Cu(II) and Zn(II)] has also been synthesized. The formation of the Schiff base ligand (L) and its complexes have been envisaged from IR, 1H and 13C NMR studies. The absorption band observed in the electronic spectra and magnetic moment values confirm an octahedral environment around the metal ion. The molar conductivity measurements confirm the non-ionic character of these complexes. Fluorescence and UV–Vis absorption studies performed on the Cu(II) complex revealed a significant binding ability to DNA.

Graphical abstractA series of mononuclear complexes of the Schiff base ligand 1,2-diaminophenyl-N,N′-bis-(2-pyridinecarboxaldimine) has been synthesized and characterized on the basis of various spectroscopic studies. Fluorescence and absorption measurement studies on the Cu(II) complex showed an excellent binding ability to DNA.Figure optionsDownload full-size imageDownload as PowerPoint slide