| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1335700 | Polyhedron | 2016 | 5 Pages |
In this study, tris(4-carboxy-3-benzyl-3-azabutyl) amine—a novel polyaminocarboxylate ligand—was synthesized. Two new nonionic complexes (a mononuclear complex and a dinuclear complex) of gadolinium with this ligand were also synthesized as potential magnetic resonance imaging (MRI) contrast agents. The structure of the dinuclear complex was determined by X-ray crystal structure analysis. The relaxivity and cytotoxicity of the mono- and dinuclear complexes were evaluated.
Graphical abstractA mononuclear complex and a dinuclear complex of gadolinium with tris(4-carboxy-3-benzyl-3-azabutyl) amine ligand were synthesized. The structure of the dinuclear complex was determined by X-ray crystal structure analysis.Figure optionsDownload full-size imageDownload as PowerPoint slide
