Article ID Journal Published Year Pages File Type
1339548 Polyhedron 2010 7 Pages PDF
Abstract
The DNA cleavage activities of four closely related Schiff base macrocyclic oxamido nickel(II) complexes NiL1 ∼ NiL4 are compared. In the absence of any added redox cofactors, NiL3 can cleavage DNA effectively. There are O-H⋯O hydrogen bonds and Ni⋯O and Ni⋯L van der Waals forces in the crystal structure of NiL3 methanol solvate. The DNA cleavage kinetics of NiL3 has been studied in detail.
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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