Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
13426328 | Schizophrenia Research | 2019 | 6 Pages |
Abstract
We addressed the relationship between white matter architecture, represented by MRI fractional anisotropy (FA), and cognition in individuals with first-episode psychosis (FEP) by applying for a new methodology that allows whole brain parcellation of core and peripheral white matter in a biologically meaningful fashion. Regionally specific correlations were found in FEP between three specific domains of cognition (processing speed, attention/working memory, and executive functioning) and FA at the deep (cerebral peduncles, sagittal striatum, uncinate, internal/external capsule, cingulum) and peripheral white matter (adjacent to inferior temporal, angular, supramarginal, insula, occipital, rectus gyrus).
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Authors
Andreia V. Faria, Jeffrey Crawford, Chenfei Ye, Johnny Hsu, Anshel Kenkare, David Schretlen, Akira Sawa,