One-pot and two-step synthesis of novel carbonylthioureas and dicarbonyldithioureas derivatives

•The new compounds of thioureas and dithioureas derivatives are synthesized.•The crystal structure one of these compounds was determined by X-ray crystallography.•The hydrogen bonding patterns in crystal structure are investigate.•All synthesized compounds were evaluated for antibacterial activity.

One-pot, two-step synthesis of several 1-cyclopropanecarbonyl-3-(substituted phenyl)-thioureas and 1-(phenylene-1,4-dione)-3,3′-(substituted phenyl)-dithioureas have been successfully prepared. The structures of the synthesized compounds were confirmed by elemental analysis, FT-IR spectroscopy and NMR. Also the crystal structure one of these compounds was determined by X-ray crystallography. All synthesized compounds were evaluated for antibacterial activity using Salmonella enterica (SE), Micrococcus luteus (ML), Bacillus subtilis (BS) and Pseudomonas aeruginosa (PS).