Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1401994 | Journal of Molecular Structure | 2015 | 6 Pages |
•We report microwave-assisted synthesis of new hydroxycoumarin derivatives.•The structures of new compounds were studied with X-ray diffraction technique.•The solid state structure was analyzed using the fully resolved 13C CP/MAS.
5-[2-(N,N-diethylamino)ethoxy]-4,7-dimethylcoumarin (1) and 6-acetyl-5-[2-(N,N-diethylamino)ethoxy]-4,7-dimethylcoumarin (2) were synthesized in a traditional way and microwave-assisted synthesis. Crystals of 2 in form of hydrochloride salt (3) were investigated using single crystal X-ray diffraction technique. In the crystal lattice of 3 there is only one type of strong hydrogen bond present involving protonated amino group and chloride anion. The whole structure is dominated by weak C–H…Cl−, C–H…O contacts. There is also visible aggregation of cations in stacks due to π–π interactions. The solid state structures of 1 and 2 derived from 13C CP/MAS NMR spectra were also proposed.
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