Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1402995 | Journal of Molecular Structure | 2013 | 5 Pages |
•Synthesis of a new palladium(II) complex with coumarine-derived ligand.•Crystal structure of palladium(II) complex.•Cytotoxicity of obtained compounds.
The new coumarine derivative, 4-hydroxy-3-(1-(p-tolylimino)ethyl)-2H-chromen-2-one, and corresponding palladium(II) complex have been synthesized and characterized by microanalysis, infrared, 1H and 13C NMR spectroscopy. The proposed structure of the complex was confirmed on the basis of an X-ray structural study. In vitro antitumor activity for the ligand and complex was investigated.
Graphical abstractThe new coumarine derivative, 4-hydroxy-3-(1-(p-tolylimino)ethyl)-2H-chromen-2-one, and corresponding palladium(II) complex have been synthesized and characterized by microanalysis, infrared, 1H and 13C NMR spectroscopy. The proposed structure of the complex was confirmed the basis of an X-ray structural study. In vitro antitumor activity for the ligand and compex was investigated.Figure optionsDownload full-size imageDownload as PowerPoint slide