Article ID Journal Published Year Pages File Type
1403345 Journal of Molecular Structure 2013 4 Pages PDF
Abstract

Diffusion ordered spectroscopy (DOSY) generally fails to separate the peaks pertaining to isomeric species possessing identical molecular weights and similar hydrodynamic radii. The present study demonstrates the resolution of isomers using α/β-cyclodextrin as a co-solute by Matrix Assisted Diffusion Ordered Spectroscopy. The resolution of isomers has been achieved by measuring the significant differences in the diffusion rates between the positional isomers of aminobenzoic acids, benzenedicarboxylic acids and between the cis, trans isomers, fumaric acid and maleic acid.

► Separation of constitutional isomers. ► Diffusion ordered spectroscopy. ► Two dimensional NMR experiments. ► α and β-Cyclodextrin. ► Separation of complex mixtures.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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