Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1405944 | Journal of Molecular Structure | 2012 | 7 Pages |
In the present study, the synthesis and liquid phase extraction properties towards some amino acid methylesters and amino alcohols of Schiff base and amino alcohol substituted calix[4]arene are reported. The Schiff base substituted calix[4]arene 5 has been synthesized via condensation reaction involving 5,17-diformyl-11,23-di-tert-butyl-25,27-di[3-(4-formylphenoxy)propoxy]-26,28 dihydroxycalix[4]arene 4 and (R)-(−)-2-phenylglycine methyl ester in CHCl3:MeOH. To give the amino alcohol substituted calix[4]arene 6, the synthesized chiral compound 5 was reduced by LiAlH4. The new chiral Schiff base and amino alcohol derivatives of calix[4]arene have been characterized by a combination of FT-IR, 1H NMR, 13C NMR, FAB-MS and elemental analysis. Also, the extraction behaviors of 5 and 6 towards some selected amino acid methylesters and amino alcohols have been studied by liquid–liquid extraction.
s► The novel chiral derivatives of calix[4]arene were synthesized in the present study. ► The chiral calix[4]arenes were characterized using FT-IR,1H NMR,13C NMR,FAB-MS. ► The chiral recognition properties of chiral calix[4]arenes were also investigated.