| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1406334 | Journal of Molecular Structure | 2011 | 5 Pages |
Abstract
Betulin and the related compounds found in the outer bark of the birch tree have attached an increasing interest in the pharmaceutical formulation, due to their anti-cancer activity. Betulin exhibits a very poor solubility; therefore new approaches are required, such as the preparation of the guest–host type complexes using cyclodextrins. The new prepared betulin – hydroxy-propyl-gamma-cyclodextrin (HPGCD) complexes have been obtained and characterized using vibrational spectroscopic techniques in conjunction with quantum chemical calculation.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
A. Falamaş, S. Cînta Pînzaru, V. Chiş, C. Dehelean,