Article ID Journal Published Year Pages File Type
1406719 Journal of Molecular Structure 2010 6 Pages PDF
Abstract

A novel host–guest inclusion complex MAH-β-CD–APAP (MAH-β-CD = a modified β-cyclodextrin carrying seven vinyl carboxylic acid groups; APAP = 4-Acetamino phenol) was prepared. Its structure was characterized by 1H NMR, 13C NMR, IR spectra, thermogravimetric analysis (TGA) and elementary analysis. The results showed that APAP was encapsulated within the MAH-β-CD cavity. Moreover, the important phase solubility studies were carried out, which demonstrated a water-soluble inclusion complex was formed. From the phase-solubility diagram, the stoichiometry and the apparent stability constant (K1:1) were obtained to be 1:1 and 1.43 × 103 L/mol, respectively.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , ,