Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1406839 | Journal of Molecular Structure | 2010 | 5 Pages |
Abstract
The solid-state complexes between para-sulphonato-calix[4]arene and the drugs tamoxifen and tetracaine show an unusual 4:1 guest-host stoichiometry with formation of hydrophobic layer of drug molecules held between bilayers of para-sulphonato-calix[4]arene. In both structures each of the four independent drug molecules adopts different conformation due to the different mode of interaction with the anionic host, the neighbouring drug cations and water molecules.
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Authors
Oksana Danylyuk, Melany Monachino, Adina N. Lazar, Kinga Suwinska, Anthony W. Coleman,