| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1407746 | Journal of Molecular Structure | 2007 | 7 Pages |
Abstract
The binding of flavonoids (quercetin and myricetin) to catalase was investigated by fluorescence and circular dichroism (CD) techniques under physiological conditions. The binding parameters and binding mode between flavonoids and catalase were determined, and the results of synchronous fluorescence spectra and CD indicated a conformational change of catalase with addition of flavonoids. The effect of both Cu2+ and vitamin C on the binding constant of flavonoid-catalase was also examined. The experiment data show that the difference of the structure characteristics of quercetin and myricetin has a significant effect on their binding affinity for catalase.
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Authors
Jingfeng Zhu, Xia Zhang, Daojin Li, Jing Jin,