Conformation of the umifenovir cation in the molecular and crystal structures of four carboxylic acid salts

•Umifenovir carboxylic acid salt crystals have been prepared.•Structures of maleate, salicylate, salicylate chloroform solvate, glutarate and gentisate are reported.•Conformation changes of the umifenovir moiety as a result of salt formation have been determined.

The umifenovir salts of maleic, salicylic, glutaric, and gentisic acid as well as the chloroform solvate of the salicylate were prepared. Single crystals of the five compounds were obtained and their molecular and crystal structures determined by X-ray diffraction. In each structure the conformation of phenyl ring with respect to the indole group of the umifenovir moiety is different. The water solubility and melting points of the studied umifenovir salts have been determined.

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