| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1408776 | Journal of Molecular Structure | 2013 | 6 Pages |
The healing effect of BPC 157 on rat femoral head osteonecrosis was monitored by Raman spectroscopy. Three groups of rats were defined: an injured group treated with BPC 157 (10 μg/kg/daily ip), an injured control group (treated with saline, 5 ml/kg/daily ip), and an uninjured healthy group. The spectra were recorded and the healing effect assessed on samples harvested from animals which were sacrificed 3 and 6 weeks after being injured. The statistical analysis of the recorded spectra showed statistical differences between the BPC 157-treated, control, and healthy groups of animals. In particular, after 6 weeks the spectral resemblance between the healthy and BPC 157 samples indicated a positive BPC 157 influence on the healing process of rat femoral head.
• Healing process monitored with Raman spectroscopy. • Healing of osteonecrotic femoral head. • BPC 157 treatment. • Statistical analysis of recorded spectra. • Student t-test and principal component analysis.
