Novel decavanadate cluster complexes [H2V10O28][LH]4·nH2O (L = Imidazole, n = 2 or 2-methylimidazole, n = 0): Preparation, characterization and genotoxic studies

The title complexes were obtained from the reaction of VOSO4 with imidazole or 2-methyl imidazole in presence of adipic acid/iminodiacetic acid. X-ray crystallographic investigations on [H2V10O28](2-MeImzH)4 (2) revealed a strong interaction between decavanadate anion and the protonated ligand moieties as counter cations to stabilize the crystal motif resulting in a high symmetry 2D sheet network. The cyclic voltammetry of (2) suggested formation of a quasi-reversible redox (VV/IV) couple in the solution. The genotoxic studies employing single cell gel electrophoresis (comet assay) confirmed the non-toxic nature of the compounds.

► The present work describes synthesis and characterization of novel decavanadate complexes. ► The chemistry of guest [H2V10O28]4− anion and host [LH]+ (L = imidazole or 2-methyl imidazole) cations has been developed. ► X-ray crystallographic studies support a regular 2D stacking via H-bonding. ► The CV of the complex (2) has been discussed. ► The genotoxic properties were also assessed.