Article ID Journal Published Year Pages File Type
1409415 Journal of Molecular Structure 2011 6 Pages PDF
Abstract

The crystallization of 3-pyridyl (1) and 4-pyridyl (2) analogues of the title compound results in different crystalline hydrates and polymorphs and their crystal structures reveal that 1 and 2 exhibit conformational isomerism. The molecule 1 forms three crystalline forms from MeOH solution depending on concentration of the solution. Among these three forms, two are polymorphic monohydrates. However, the crystallization of 2 was found to be dependent on the solvent of crystallization and resulted in new crystalline form from DMF as a dihydrate. The hydrates of both 1 and 2 can be classified as isolated site hydrates. In these crystal structures, water molecules found to exhibit three types of coordination environments with regard to hydrogen bonds.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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