| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1409954 | Journal of Molecular Structure | 2010 | 6 Pages |
Abstract
A molecular electrostatic potential (MEP) map was used in an attempt to identify key features of the kamebacetal A to account for its anti-tumor activity. MEP investigations reveal that compound 1, which shows anti-tumor activity, possesses electron-rich regions that extend over the hydroxyl and carbonyl groups of compound 1. The data generated in this study is valuable as it provides an insight into kamebacetal A molecular and structure-activity relationships.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tao Wang, Fu-ming Tang, Yi-Heng Zhang, Zhong Chen,