Article ID Journal Published Year Pages File Type
1410082 Journal of Molecular Structure 2011 6 Pages PDF
Abstract

The crystal structure of the title compound, 4b,9b-dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione has been determined by single crystal X-ray diffraction. It crystallizes in the monoclinic space group P21/c with Z = 4. The FTIR as well as the 1H and 13C NMR spectra of the compound were also recorded and briefly discussed. The compound showed potential antimicrobial activity comparable to that of clinically used antimicrobial agents against selected microorganisms. It has selective and moderate inhibitory activity on butyryl cholinesterase enzyme and could serve as potential lead compound for synthesis of more bioactive derivatives.

► 4b,9b-Dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione monohydrate was synthesized. ► X-ray crystallography, 1H, 13C NMR and IR spectral studies confirmed the structure. ► X-ray studies showed twofold linkages of neighboring units via intermolecular hydrogen bonds. ► Potential antimicrobial activity and moderate inhibitory activity.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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