| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1411628 | Journal of Molecular Structure | 2009 | 6 Pages |
Abstract
Popular chiral drugs, guaifenesin, methocarbamol, and mephenesin were investigated by single-crystal X-ray analysis both for enantiopure and racemic samples. The absolute configurations for all substances were established through Flack parameter method. The conglomerate-forming nature for the compounds was confirmed by equivalence of crystal characteristics of enantiopure and racemic samples. The molecular structures and crystal packing details were evaluated and compared with one another for all three investigated substances.
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Authors
Alexander A. Bredikhin, Aidar T. Gubaidullin, Zemfira A. Bredikhina, Dmitry B. Krivolapov, Alexander V. Pashagin, Igor A. Litvinov,