Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
14343 | Biotechnology Advances | 2013 | 7 Pages |
Abstract
Genome engineering has been developed to create useful strains for biological studies and industrial uses. However, a continuous challenge remained in the field: technical limitations in high-throughput screening and precise manipulation of strains. Today, technical improvements have made genome engineering more rapid and efficient. This review introduces recent advances in genome engineering technologies applied to Escherichia coli as well as multiplex automated genome engineering (MAGE), a recent technique proposed as a powerful toolkit due to its straightforward process, rapid experimental procedures, and highly efficient properties.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Jaehwan Jeong, Namjin Cho, Daehee Jung, Duhee Bang,