Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
14619 | Biotechnology Advances | 2011 | 14 Pages |
Abstract
2,3-Butanediol is a promising bulk chemical due to its extensive industry applications. The state-of-the-art nature of microbial 2,3-butanediol production is reviewed in this paper. Various strategies for efficient and economical microbial 2,3-butanediol production, including strain improvement, substrate alternation, and process development, are reviewed and compared with regard to their pros and cons. This review also summarizes value added derivatives of biologically produced 2,3-butanediol and different strategies for downstream processing. The future prospects of microbial 2,3-butanediol production are discussed in light of the current progress, challenges, and trends in this field. Guidelines for future studies are also proposed.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Xiao-Jun Ji, He Huang, Ping-Kai Ouyang,