| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 15985 | Current Opinion in Biotechnology | 2008 | 7 Pages |
Abstract
Many biological events are binary. The switch between mutually exclusive OFF to ON state in response to a stimulus is frequently mediated by a control circuit with a positive and/or a negative feedback. Such a system typically exhibits hysteresis with its switching ON and OFF stimulus levels dependent on the current state of the system. The system can be shown to be bistable both experimentally and mathematically. Work to synthesize such switches by combining natural or engineered components has begun to illustrate the potential of such control circuits in many areas of applications.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Anushree Chatterjee, Yiannis N. Kaznessis, Wei-Shou Hu,