Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
170585 | Comptes Rendus Chimie | 2015 | 4 Pages |
Abstract
A concise, facile and straightforward synthetic method has been described for the synthesis of 2-(3-amino-2-oxoindolin-3-yl)-3-hydroxynaphthalene-1,4-dione derivatives by a one-pot, three-component reaction of isatins, 2-hydroxy-1,4-naphthoquinone and ammonium acetate under catalyst-free conditions in ethanol. This protocol becomes highly efficient due to its mild reaction conditions, operational simplicity, and overall good to excellent yields (80–99%).
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Authors
Fengfeng Che, Yongsheng Wang, Tianhua Shen, Xiaoxia An, Qingbao Song,