Article ID Journal Published Year Pages File Type
1785626 Current Applied Physics 2015 4 Pages PDF
Abstract

•We used polarization dependent THz spectroscopy.•Normal scleral tissue is polarization sensitive, but cross-linked tissue is not.•A simple theoretical modeling based on the Drude model was used.•Our study reveals that THz spectroscopy is a tool for studying biological tissues.

Structural properties of human scleral tissues are investigated using polarization-dependent terahertz time-domain spectroscopy. Cross-linked tissue shows polarization-independent transmission properties, whereas normal tissue is polarization-dependent. This results from the different structural arrangements of the collagen fibrils that compose the human scleral tissues. In cross-linked tissue, collagen fibrils structurally form interlocking arrangements, unlike the regular parallel arrangement found in normal tissue. Our results demonstrate that terahertz spectroscopy is a powerful tool for investigating the structural characteristics of biological tissues and systems.

Related Topics
Physical Sciences and Engineering Physics and Astronomy Condensed Matter Physics
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