Article ID Journal Published Year Pages File Type
1787353 Current Applied Physics 2011 6 Pages PDF
Abstract

Magnetic nanoparticles (MNPs) were modified by polyaspartate (PAA) and poly(ethyleneimine) (PEI) via Layer-by-Layer self-assembly. Two steps were involved in: the first was to coat MNPs by PAA at pH = 6; the second was to coat the former by PEI. The successful surface modification of MNPs was confirmed using X-ray photoelectron spectroscopy (XPS), thermogravimetric analysis (TGA) and fourier transform infrared (FTIR) measurements. The modified MNPs interact strongly with negative fibrinogen and weakly with neutral γ-globin and positive lysozyme.

► Magnetic nanoparticles were modified via Layer-by-Layer self-assembly. ► The nonspecific adsorption of protein on MNPs was resisted. ► The modified MNPs interact strongly with negative fibrinogen. ► The modified MNPs interact weakly with neutral γ-globin and positive lysozyme.

Related Topics
Physical Sciences and Engineering Physics and Astronomy Condensed Matter Physics
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