Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1789204 | Current Applied Physics | 2006 | 5 Pages |
Abstract
This research aims to develop DNA chip array without an indicator. We fabricated microelectrode array by photolithography technology. Several DNA probes were immobilized on an electrode. Then, target DNA was hybridized and measured electrochemically. Cyclic-voltammograms (CVs) showed a difference between DNA probe and mismatched DNA in an anodic peak. This indicator-free DNA chip resulted in a sequence-specific detection of the target DNA.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Yong-Sung Choi, Kyung-Sup Lee, Dae-Hee Park,