Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
178992 | Electrochemistry Communications | 2014 | 4 Pages |
Abstract
A novel label-free plasmonic-based electrochemical impedance platform with multiple optical and electrochemical signals, including conventional surface plasmon resonance (SPR), amplitude/phase shift of ac SPR and admittance, was described in this work. We utilize conventional SPR and admittance amplitude to detect the K+ ion induced G-quadruplexes assembly. In particular, the admittance amplitude detects interfacial capacitance related to DNA conformation change, which has better performance to K+ ion than conventional SPR. Meanwhile, we demonstrate phase shift of ac SPR as a more sensitive parameter to detect charge status of DNA in different pH solutions.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Jin Lu, Jinghong Li,