Article ID Journal Published Year Pages File Type
179704 Electrochemistry Communications 2012 4 Pages PDF
Abstract

An electrochemical sensor for the sensitive determination of guanine has been developed, which is based on the electrodeposition of a nanostructured platinum thin film on a glassy carbon electrode. The effects of the electrodeposition time of the platinum thin film, pH, square-wave frequency and electroactive interferents on the voltammetric response of the sensor were evaluated. The optimized sensor exhibited excellent performance for the detection of guanine with a high sensitivity (157.8 nA μM− 1), a low detection limit (3.1 × 10− 8 M), a wide linear range (0.1–500 μM), as well as good reproducibility, stability, and selectivity.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Nanostructured Pt thin film on GCE exhibited fast electron transfer rate. ► New Pt/GCE electrochemical sensor designed for the determination of guanine. ► High analytical performance with low detection limit and high sensitivity. ► The designed guanine sensor has promising biomedical and clinical applications.

Related Topics
Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
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