Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
179704 | Electrochemistry Communications | 2012 | 4 Pages |
An electrochemical sensor for the sensitive determination of guanine has been developed, which is based on the electrodeposition of a nanostructured platinum thin film on a glassy carbon electrode. The effects of the electrodeposition time of the platinum thin film, pH, square-wave frequency and electroactive interferents on the voltammetric response of the sensor were evaluated. The optimized sensor exhibited excellent performance for the detection of guanine with a high sensitivity (157.8 nA μM− 1), a low detection limit (3.1 × 10− 8 M), a wide linear range (0.1–500 μM), as well as good reproducibility, stability, and selectivity.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Nanostructured Pt thin film on GCE exhibited fast electron transfer rate. ► New Pt/GCE electrochemical sensor designed for the determination of guanine. ► High analytical performance with low detection limit and high sensitivity. ► The designed guanine sensor has promising biomedical and clinical applications.