Article ID Journal Published Year Pages File Type
179732 Electrochemistry Communications 2012 4 Pages PDF
Abstract

We compared the differential pulse voltammetric performance of various chemically modified graphenes (CMGs) to those of glassy carbon (GC) and edge plane pyrolytic graphite (EPPG), using a biologically important analyte, uric acid. Analytical parameters of sensitivity, linearity, repeatability and selectivity were considered. Graphite oxide, graphene oxide, chemically reduced graphene oxide, electrochemically reduced graphene oxide and thermally reduced graphene oxide (TR-GO) were studied. TR-GO showed the highest sensitivity and selectivity, but among the poorest linearity and reproducibility. The other CMGs generally demonstrated more sensitive but less selective and reproducible responses than GC and EPPG. These results will enhance our understanding of the applicability of CMGs in biosensing.

► DPV performance of various chemically modified graphenes (CMGs) was studied. ► Comparison of CMGs to those of GC and EPPG is made using uric acid. ► Analytical parameters of sensitivity, linearity, repeatability and selectivity considered. ► Responses of CMGs are more sensitive but less selective than GC and EPPG.

Related Topics
Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
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