Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
180174 | Electrochemistry Communications | 2010 | 4 Pages |
Abstract
Highly reproducible bioelectrocatalytic endpoint assays are described. The method is based on a complete redox conversion of a substrate to a redox mediator with a corresponding redox enzyme and an amperometric detection of the reduced mediator on a diffusionally independent microelectrode array. The current reaches a steady state within a few seconds and is proportional to the number of the integrated microelectrodes. The method has successfully been applied to histamine detection at micro-molar level and glucose detection at milli-molar level.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Tatsuo Noda, Katsumi Hamamoto, Maiko Tsutsumi, Seiya Tsujimura, Osamu Shirai, Kenji Kano,