Article ID Journal Published Year Pages File Type
180174 Electrochemistry Communications 2010 4 Pages PDF
Abstract

Highly reproducible bioelectrocatalytic endpoint assays are described. The method is based on a complete redox conversion of a substrate to a redox mediator with a corresponding redox enzyme and an amperometric detection of the reduced mediator on a diffusionally independent microelectrode array. The current reaches a steady state within a few seconds and is proportional to the number of the integrated microelectrodes. The method has successfully been applied to histamine detection at micro-molar level and glucose detection at milli-molar level.

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Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
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