Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
180757 | Electrochemistry Communications | 2009 | 4 Pages |
Abstract
The integration of electrochemical-based biolithography (ECBL) with an ordinary atomic force microscope (AFM) enables in situ lithography adjacent to a single, cultured cell, consequently allowing the morphological shape of the cell to be manipulated. The tip of a commercially available AFM cantilever was modified to serve as an electrode that could generate the oxidant HBrO for local, controlled etching of a cytophobic material (heparin or albumin) previously layered adjacent to a living cell. A NIH-3T3 fibroblast, initially confined to a patterned area, extended along a bioadhesive surface that had been newly exposed using the ECBL-AFM system.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Soichiro Sekine, Hirokazu Kaji, Matsuhiko Nishizawa,