| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 180982 | Electrochemistry Communications | 2010 | 4 Pages |
Abstract
A simple self-powered drug delivery system was developed based on the galvanic cell mechanism, involving the direct deposition of a drug-contained polypyrrole (PPy) film on the one side of a titanium foil. After covering the other side with a eicosane-poly(l-lactide) (PLLA) blend film, it is interesting to observe that massive drug release only occurred when the release medium was heated to the body temperature. The methyltetrazolium (MTT) assay indicated that the system had good biocompatibility. Since titanium is one of the most commonly used load-bearing implant materials, it is expected that the present drug delivery system can find applications in titanium-related orthopaedic fields.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Dongtao Ge, Rucai Qi, Jing Mu, Xiaoning Ru, Shimin Hong, Shan Ji, Vladimir Linkov, Wei Shi,