Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1884557 | Radiation Physics and Chemistry | 2008 | 6 Pages |
Abstract
The erythrocyte suspensions in Na-phosphate buffered isotonic NaCl solution (PBS) or Na-phosphate isotonic buffer (PB) (hematocrit 1%) were irradiated with the dose of 400 Gy under N2O. Erythrocytes were incubated in the medium in which the cells were irradiated or in fresh PBS. The level of damage to cells was estimated on the basis of the course of post-radiation hemolysis and hemoglobin (Hb) oxidation. The medium in which the cells were irradiated and incubated influenced the course of the post-radiation hemolysis and Hb oxidation as well as some other parameters. We discussed the contribution of hydroxyl and chloride radicals in the initiation of erythrocyte damage and oxygen modification of these processes.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Anita Krokosz, Magdalena A. Komorowska, Zofia Szweda-Lewandowska,