Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1884654 | Radiation Physics and Chemistry | 2007 | 4 Pages |
Abstract
Enterobacter sakazakii has been implicated as a causal organism in a severe form of neonatal meningitis, with reported mortality rates of 20%. The population at greatest risk is immunocompromised infants of any age. Dried infant formula has been identified as a potential source of the organism in both outbreaks and sporadic cases. The objective of this study was to investigate theirradiation effect of the inactivation on E. sakazakii (ATCC 29544) of a dehydrated infant formula. The D10-values were 0.22-0.27 and 0.76 kGy for broth and dehydrated infant formula, respectively. The irradiation at 5.0 kGy was able to completely eliminate the E. sakazakii inoculated at 8.0 to 9.0 log CFU gâ1 onto a dehydrated infant formula. There was no regrowth for all samples during the time they were stored at 10 °C for 6 h after rehydration. The present results indicated that a gamma-irradiation could potentially be used to inactivate E. sakazakii in a dehydrated powdered infant formula.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Ju-Woon Lee, Sang-Hee Oh, Eui-Baek Byun, Jae-Hun Kim, Jang-Ho Kim, Jae-Ho Woon, Myung-Woo Byun,