Article ID Journal Published Year Pages File Type
1886219 Radiation Physics and Chemistry 2013 6 Pages PDF
Abstract

•SSS was successfully grafted onto PPNWF via co-irradiation method with the addition of NVP.•The grafting kinetics was studied and the anchored chains did enhance the wettability of PPNWF.•The modified PPNWF presented good blood compatibility and excellent anticoagulation activity.

Sodium styrenesulfonate was grafted onto PPNWF via γ-ray co-irradiation method with the existence of N-vinyl-2-pyrrolidone. The effect of absorbed dose, dose rate and concentration of binary monomer on the degree of grafting was investigated. The surface chemical change was characterized by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray photoelectron spectroscopy (XPS). The wettability was characterized through the measurement of adsorption percentage of water and phosphate buffer solution (PBS). The result demonstrated that the grafted poly(NVP–co-SSS) chains can improve the hydrophilicity of PPNWF. Furthermore, the modified PPNWF has good blood compatibility, such as low hemolysis rate, low platelet adhesion and effectively extending the blood coagulation times. Consequently, hydrophilicity and hemocompatibility of PPNWF were greatly enhanced by the immobilization of poly(NVP–co-SSS) chains.

Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
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