Article ID Journal Published Year Pages File Type
1889022 Chaos, Solitons & Fractals 2014 9 Pages PDF
Abstract
In this article we study the dynamical behaviour of a intracellular delayed viral infection with immune impairment model and general non-linear incidence rate. Several techniques, including a non-linear stability analysis by means of the Lyapunov theory and sensitivity analysis, have been used to reveal features of the model dynamics. The classical threshold for the basic reproductive number is obtained: if the basic reproductive number of the virus is less than one, the infection-free equilibrium is globally asymptotically stable and the infected equilibrium is globally asymptotically stable if the basic reproductive number is higher than one.
Related Topics
Physical Sciences and Engineering Physics and Astronomy Statistical and Nonlinear Physics
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