Article ID Journal Published Year Pages File Type
1897422 Physica D: Nonlinear Phenomena 2010 5 Pages PDF
Abstract
A transcriptional modular network cascade with general activation/repression coupling is analysed. It is shown that in certain conditions (the Hill coefficient is unity) it is equivalent to a cascade made of the same type of gene, and moreover the dynamics is linearisable. The protein production is shown to be a travelling kink wave on the cascade showing a successive gene expression along it. Also a cellular automaton description for both open and closed (plasmid) cascades is provided.
Related Topics
Physical Sciences and Engineering Mathematics Applied Mathematics
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