| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1906402 | Experimental Gerontology | 2012 | 9 Pages |
Abstract
⺠JD-30 improves spatial recognition impairment and LTP reduction of SAMP8. ⺠JD-30 protects the neuron from damage. ⺠JD-30 decreases β-amyloid content and deposition. ⺠JD-30 is a neuroprotective against age-related senescence. ⺠JD-30 is a potential therapeutic agent for AD treatment.
Keywords
GAPDHHFSSAMP8IODAPPAβBACE1DSSCatBβ-Amyloidβ-Amyloid (Aβ)insulin degrading enzymePopulation spikeIDEAlzheimer's diseaseAlzheimer's disease (AD)integrated optical densitylong-term potentiationLTPdentate gyrusNEPNeprilysinpolymerase chain reactionPCRLong-term potentiation (LTP)Amyloid protein precursorCathepsin BGlyceraldehyde phosphate dehydrogenaseSpatial learning and memory
Related Topics
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Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Zeng-Yao Hu, Gang Liu, Xiao-Rui Cheng, Yan Huang, Sheng Yang, Shan-Yi Qiao, Lei Sun, Wen-Xia Zhou, Yong-Xiang Zhang,