Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1917001 | Maturitas | 2016 | 17 Pages |
Abstract
Newly developed treatment strategies for breast cancer have reduced mortality rates over the past decades. Patients with breast cancer represent a heterogeneous population. Differences in the severity of the disease require diverse treatment options. Women have distinct individual risk patterns for cardiovascular disease that may affect their susceptibility to cardiotoxicity during therapy. While breast cancer treatment is targeted more on tumor and patient characteristics, a tailored individual approach with early and late cardiosurveillance is not yet implemented in routine care. Newly available cardiac imaging techniques are better suited to the early detection of cardiotoxicity and should be used more often in those patients at highest risk, as the early intervention afforded will improve their quality of life and prognosis.
Keywords
GLSHFpEFSERMVTEACEDCISAngiotensin converting enzyme inhibitorsEuropean Society of CardiologyLeft ventricularcardiovascular diseaseESCCVDBreast cancerCardiotoxicityCardiovascular toxicityVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Global longitudinal strainSelective estrogen receptor modulatorAromatase inhibitorsHeart failure with preserved ejection fractionDuctal carcinoma in situ
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Authors
Angela H.E.M. Maas, Nelleke Ottevanger, Femke Atsma, Maarten J. Cramer, Tim Leiner, Philip Poortmans,